A Combinative Assembly Strategy Inspired Reversibly Borate-Bridged Polymeric Micelles for Lesion-Specific Rapid Release of Anti-Coccidial Drugs
نویسندگان
چکیده
منابع مشابه
Multifunctional polymeric micelles for delivery of drugs and siRNA
Polymeric micelles, self-assembling nano-constructs of amphiphilic copolymers with a core-shell structure have been used as versatile carriers for delivery of drugs as well as nucleic acids. They have gained immense popularity owing to a host of favorable properties including their capacity to effectively solubilize a variety of poorly soluble pharmaceutical agents, biocompatibility, longevity,...
متن کاملChaotropic-anion-induced supramolecular self-assembly of ionic polymeric micelles.
Traditional micelle self-assembly is driven by the association of hydrophobic segments of amphiphilic molecules forming distinctive core-shell nanostructures in water. Here we report a surprising chaotropic-anion-induced micellization of cationic ammonium-containing block copolymers. The resulting micelle nanoparticle consists of a large number of ion pairs (≈60,000) in each hydrophobic core. U...
متن کاملCo-assembly of Patchy Polymeric Micelles and Protein Molecules.
The development in the synthesis and self-assembly of patchy nanoparticles has resulted in the creation of complex hierarchical structures. Co-assembly of polymeric nanoparticles and protein molecules combines the advantages of polymeric materials and biomolecules, and will produce new functional materials. Co-assembly of positively charged patchy micelles and negatively charged bovine serum al...
متن کاملAssembly of a Tripeptide and Anti-Inflammatory Drugs into Supramolecular Hydrogels for Sustained Release
Supramolecular hydrogels offer interesting opportunities for co-assembly with drugs towards sustained release over time, which could be achieved given that the drug participates in the hydrogel nanostructure, and it is not simply physically entrapped within the gel matrix. DLeu-Phe-Phe is an attractive building block of biomaterials in light of the peptide’s inherent biocompatibility and biodeg...
متن کاملEpigenetic drugs: a novel anti-aging strategy?
Aging is a natural phenomenon which is peculiar to all living organisms. However, it is believed by some scientists that senescence could be postponed or prevented by certain approaches. Some dietary ingredients and supplements have been suggested to have anti-aging and life-extending effects. Natural and synthetic dietary supplements including anti-oxidants, vitamins, and hormones are among th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nano-Micro Letters
سال: 2020
ISSN: 2311-6706,2150-5551
DOI: 10.1007/s40820-020-00495-1